Ever wonder why, despite eating red meat and taking B12 supplements, you still feel fatigued, or your B12 levels remain low? This is a common concern among BluZone clients, and the answer often lies in how your body processes and methylates these vital nutrients.
What Is B Complex with Folate?
A B complex supplement contains all the B vitamins—B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6, B7 (biotin), B9 (folate), and B12. When combined with folate, this complex can support energy, mood, and overall health. Folate, the natural form of vitamin B9, is crucial for DNA production and repair, while B12 supports nerve health and red blood cell formation.
What Is Methylation, and Why Is It Important?
Methylation is a crucial biochemical process that occurs in every cell of your body. It involves adding a methyl group (a carbon atom linked to three hydrogen atoms) to various molecules, including DNA, proteins, and hormones. Proper methylation is vital for:
- DNA repair and gene expression
- Detoxification
- Hormone regulation
- Mental clarity and mood stability
Why Do Some People Not Methylate B12 Effectively?
Many individuals have genetic variations—most notably mutations in the MTHFR gene—that impair their ability to methylate efficiently. If you have this or similar genetic variants, your body may struggle to convert inactive or synthetic forms of B12 and folate into their active, methylated forms. This can lead to:
- Persistently low B12 levels despite dietary intake
- Elevated homocysteine levels, increasing cardiovascular risk
- Feeling tired, foggy, or lacking energy, even when you’re eating plenty of red meat or taking supplements
It’s a frustrating cycle that many BluZone clients experience—why is their B12 always deficient, despite their efforts?
Personalized Support at BluZone
At BluZone, Dr. Hope Honigsberg specializes in personalized health plans tailored to your unique biochemistry. Through blood testing, she can assess your methylation status—specifically your homocysteine levels and other markers—and determine if you have genetic variants like MTHFR that might affect your methylation.
Based on your results, Dr. Honigsberg can recommend:
- The appropriate form and dose of B12 (methylcobalamin vs. cyanocobalamin)
- The right folate (active methylfolate vs. folic acid)
- Custom dosing tailored to your specific needs
How We Can Help
We offer convenient blood work, which you can get at any local lab or pharmacy after a consultation. From there, Dr. Hope Honigsberg can review your results and develop a personalized plan to support your methylation pathways—helping you boost your energy, improve your mental clarity, and finally achieve the health benefits you’re seeking.
Take Control of Your Methylation
Don’t settle for feeling tired or deficient—understanding your unique genetic makeup and biochemical needs allows for targeted, effective treatment. Whether you need methylated B vitamins or other supportive therapies, BluZone is here to guide you with personalized care.
Schedule your blood work today and start your journey toward balanced, optimized health. Because personalized health isn’t just a goal—it’s the key to your optimized self.
- National Institutes of Health (NIH) – Vitamin B12 Fact Sheet
Comprehensive overview of B12, its functions, deficiency symptoms, and importance.
https://ods.od.nih.gov/factsheets/VitaminB12-Consumer/ - Mayo Clinic – Vitamin B12 (Cobalamin) Overview
Details on B12 deficiency symptoms, causes, and supplementation guidance.
https://www.mayoclinic.org/drugs-supplements-vitamin-b12/art-20363663 - NIH Office of Dietary Supplements – B12 Factsheet
Summarizes current research, dietary sources, and safety considerations.
https://ods.od.nih.gov/factsheets/VitaminB12-Consumer/ - PubMed – Scientific Research on B12 and Methylation
Research articles exploring the connection between B12, methylation, and health outcomes.
https://pubmed.ncbi.nlm.nih.gov/?term=B12+methylation - Harvard Health Publishing – Methylation and Its Impact on Health
Explains the methylation process, why it matters, and how B12 plays a role.
https://www.health.harvard.edu/blog/methylation - Dr. Hope Honigsberg & BluZone — Practice-specific resources:
- https://www.bluzonehyperbarics.com/
- Information about personalized testing, safe supplement sourcing, and lab services for B12 levels.
